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Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical...
Editeur :
Wiley-VCH
Parution :
2012-06-13
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Pharmaceuticals companies, biotech companies, and CROs, regardless of size, all face the same challenge of managing costs and operational execution associated with bringing a valuable drugs and devices to market. Because of timeline pressures and cost as well as the...
Editeur :
Academic Press
Parution :
2012-06-12
epub sans DRM
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Human interaction with the environment remains one of the most pervasive facets of modern society. In a world characterized by rapid population growth, unprecedented global trade and digital communications, energy security, natural resource scarcities, climatic changes...
Editeur :
Springer
Parution :
2012-06-08
Collection :
Emerging Topics in Ecotoxicology
ePub
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Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of...
Editeur :
Academic Press
Parution :
2012-06-07
epub sans DRM
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Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing...
Editeur :
Springer
Parution :
2012-06-07
Collection :
Experientia Supplementum
ePub
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New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover,...
Editeur :
Wiley
Parution :
2012-06-06
PDF, ePub
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Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a...
Editeur :
Wiley-VCH
Parution :
2012-06-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Asia is increasingly taking on a leading role in the fields of Good Clinical Practice (GCP) and ethics, two areas that are central to clinical research practices worldwide. Clinical research inAsia examines the evolution of these key sectors in the Asian countries where...
Editeur :
Woodhead Publishing
Parution :
2012-05-25
epub sans DRM
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The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a...
Editeur :
Wiley
Parution :
2012-05-23
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in...
Editeur :
Elsevier
Parution :
2012-05-18
epub sans DRM
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Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes, industries need to review and streamline their...
Editeur :
Wiley-VCH
Parution :
2012-05-09
PDF, ePub
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This book is meant to provide a complete overview of the research of HPV and its connection to cervical cancer.
Editeur :
Springer
Parution :
2012-04-27
ePub
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Learn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and...
Editeur :
Wiley
Parution :
2012-04-19
PDF, ePub
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A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for...
Editeur :
Wiley
Parution :
2012-04-16
PDF, ePub
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The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational...
Editeur :
Wiley
Parution :
2012-04-11
PDF, ePub
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Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and...
Editeur :
Wiley
Parution :
2012-04-11
PDF, ePub
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This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific...
Editeur :
Wiley
Parution :
2012-04-02
PDF, ePub
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Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHg’s...
Editeur :
Springer
Parution :
2012-03-23
ePub
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This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma.
Editeur :
Springer
Parution :
2012-02-28
ePub
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The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from...
Editeur :
Springer
Parution :
2012-02-25
ePub
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