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A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process....
Editeur :
Academic Press
Parution :
2012-10-18
epub sans DRM
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Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a...
Editeur :
Wiley-VCH
Parution :
2012-10-15
PDF, ePub
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Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for...
Editeur :
Academic Press
Parution :
2012-09-18
epub sans DRM
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In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have...
Editeur :
Wiley-VCH
Parution :
2012-09-13
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite...
Editeur :
Wiley-VCH
Parution :
2012-09-06
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Henipaviruses form a new genus of emerging paramyxoviruses that are the deadliest human pathogens within the Paramyxoviridae family. This volume deals with the many facets of henipavirus biology, and covers our current understanding regarding the ecology, molecular...
Editeur :
Springer
Parution :
2012-09-05
Collection :
Current Topics in Microbiology and Immunology
ePub
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This volume brings together contributions from experts in the field of Pasteurella research. Its covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of PMT and its interaction with host...
Editeur :
Springer
Parution :
2012-09-03
Collection :
Current Topics in Microbiology and Immunology
ePub
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This project follows on the success of the book "25 years of p53", published by Springer in 2006. Since this publication, there have been considerable advances on the potential application of p53 into the clinics. The goal of this book is to capture these developments...
Editeur :
Springer
Parution :
2012-08-30
ePub
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A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug...
Editeur :
Wiley
Parution :
2012-07-31
PDF, ePub
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Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The...
Editeur :
Academic Press
Parution :
2012-07-26
epub sans DRM
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This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease,...
Editeur :
Academic Press
Parution :
2012-07-24
epub sans DRM
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Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or...
Editeur :
Academic Press
Parution :
2012-07-04
epub sans DRM
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Pharmacovigilance Medical Writing covers the preparation of pharmacovigilance documents for all stages of the drug development process (i.e. from clinical development through to applications for marketing authorisations to the post-marketing stage). For each document,...
Editeur :
Wiley-Blackwell
Parution :
2012-06-22
PDF, ePub
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Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical...
Editeur :
Wiley-VCH
Parution :
2012-06-18
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Pharmaceuticals companies, biotech companies, and CROs, regardless of size, all face the same challenge of managing costs and operational execution associated with bringing a valuable drugs and devices to market. Because of timeline pressures and cost as well as the...
Editeur :
Academic Press
Parution :
2012-06-12
epub sans DRM
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Human interaction with the environment remains one of the most pervasive facets of modern society. In a world characterized by rapid population growth, unprecedented global trade and digital communications, energy security, natural resource scarcities, climatic changes...
Editeur :
Springer
Parution :
2012-06-08
Collection :
Emerging Topics in Ecotoxicology
ePub
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Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of...
Editeur :
Academic Press
Parution :
2012-06-07
epub sans DRM
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Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing...
Editeur :
Springer
Parution :
2012-06-07
Collection :
Experientia Supplementum
ePub
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New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover,...
Editeur :
Wiley
Parution :
2012-06-06
PDF, ePub
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Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a...
Editeur :
Wiley-VCH
Parution :
2012-06-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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