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Benefit-risk assessment is at the centre of the approval process for every new medicine. The ability to assess the risks of a new medicine accurately and to balance these against the benefits the medicine could bring is critical for every regulatory authority and...
Editeur :
Wiley
Parution :
2009-08-04
PDF
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Recreational drug use is a world-wide phenomenon. Despite the best efforts of governments, the public fascination with drugs shows no signs of abating. With media accounts of illegal drug use often verging on the hysterical, this book provides a refreshingly balanced...
Editeur :
OUP Oxford
Parution :
2009-07-16
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Recreational drug use is a world-wide phenomenon. Despite the best efforts of governments, the public fascination with drugs shows no signs of abating. With media accounts of illegal drug use often verging on the hysterical, this book provides a refreshingly balanced...
Editeur :
OUP Oxford
Parution :
2009-07-16
ePub
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Barrier, reservoir, target site - those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore...
Editeur :
Wiley-VCH
Parution :
2009-07-10
Collection :
Methods & Principles in Medicinal Chemistry
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Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine.
While the market is crowded with many clinical and therapeutic...
Editeur :
Academic Press
Parution :
2009-06-19
epub sans DRM
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A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability...
Editeur :
Wiley
Parution :
2009-06-17
Collection :
Wiley Series in Drug Discovery and Development
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It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and...
Editeur :
Springer
Parution :
2009-06-12
ePub
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Significance of Stem Cells to Tumor Development
Cancer stem cells remain a controversial topic and the criteria that define cancer stem cells are continuing to evolve. A recent surge in stem cell research has ignited a field of discovery into many human diseases...
Editeur :
Humana
Parution :
2009-04-20
Collection :
Cancer Drug Discovery and Development
ePub
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Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, the hypertensive disorders remain marginally studied,...
Editeur :
Academic Press
Parution :
2009-04-16
epub sans DRM
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Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and...
Editeur :
Academic Press
Parution :
2009-04-09
epub sans DRM
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This book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new technologies to help overcome the bottlenecks in developing stem cells as therapeutic agents. A key reference for...
Editeur :
Wiley
Parution :
2009-04-06
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Although there are many pharmacology texts, and electronic sources of drug information relating to GI disorders, they are frequently encyclopedic, and practical information can be difficult to find. In Pocket Handbook of GI Pharmacotherapeutics, George Wu and Achilles...
Editeur :
Humana
Parution :
2009-04-05
ePub
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This volume provides reviews of six topics demonstrating the breadth of the field and recent successes in medicinal chemistry. Each of the first five chapters takes an important biochemical target as its theme and provides an insight into current progress in drug...
Editeur :
Elsevier Science
Parution :
2009-04-01
PDF, epub sans DRM
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Addressing parasitic diseases and those caused by bacteria, this much needed reference and handbook provides a unique insight into the approach adopted by commercial science towards infectious diseases, including the work of medicinal chemists. Many of the authors are...
Editeur :
Wiley-Blackwell
Parution :
2009-03-23
PDF
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Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and...
Editeur :
Humana
Parution :
2009-03-18
Collection :
Cancer Drug Discovery and Development
ePub
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The evolution in our understanding of opioid receptors and their subtypes is in- mately linked to the development of new pharmacological treatments for diseases/ disorders as diverse as addiction, self-injurious behavior, pain, cancer, infl- mation, eating disorders,...
Editeur :
Humana
Parution :
2009-03-12
Collection :
Contemporary Neuroscience
ePub
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Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of...
Editeur :
Academic Press
Parution :
2009-03-10
epub sans DRM
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The third and final installment of Daniel J. Klionsky's new three-volume treatment of autophagy, this volume focuses on monitoring autophagy with regard to disease connections, and presents methods that can be used to analyze autophagy in clinical samples. Edited by one...
Editeur :
Academic Press
Parution :
2009-03-10
epub sans DRM
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There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose...
Editeur :
Wiley
Parution :
2009-03-04
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