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DNA topoisomerases represent an essential family ofDNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II...
Editeur :
Humana
Parution :
2011-09-21
Collection :
Cancer Drug Discovery and Development
ePub
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An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases...
Editeur :
Wiley
Parution :
2011-09-20
PDF, ePub
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The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Editeur :
Humana
Parution :
2011-09-18
Collection :
Cancer Drug Discovery and Development
ePub
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This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate...
Editeur :
Wiley
Parution :
2011-09-09
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, 'validation' of a target is not achieved until therapeutic...
Editeur :
Elsevier Science
Parution :
2011-09-02
PDF, epub sans DRM
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Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological...
Editeur :
Academic Press
Parution :
2011-09-01
epub sans DRM
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The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much current activity on the...
Editeur :
Academic Press
Parution :
2011-08-31
epub sans DRM
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Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology...
Editeur :
Academic Press
Parution :
2011-08-29
epub sans DRM
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Gastroesophageal reflux is one of the most common maladies of mankind. Approximately 40% of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug...
Editeur :
Academic Press
Parution :
2011-08-29
PDF sans DRM
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We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin”...
Editeur :
Springer
Parution :
2011-08-26
Collection :
Current Topics in Microbiology and Immunology
ePub
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Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems. This introductory guide is designed to aid the rapid understanding of the key principles of...
Editeur :
Wiley-Blackwell
Parution :
2011-08-24
ePub
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A simple and systematic guide to the planning and performance of investigations concerned with health and disease and with health care Offers researchers help in choosing a topic and to think about shaping objectives and ideas and to link these with the appropriate...
Editeur :
Wiley
Parution :
2011-08-24
PDF, ePub
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The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease.The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper...
Editeur :
Springer
Parution :
2011-08-23
ePub
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The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a...
Editeur :
Elsevier Science
Parution :
2011-08-19
epub sans DRM
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This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of...
Editeur :
Springer
Parution :
2011-08-19
Collection :
Energy Balance and Cancer
PDF, ePub
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Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of...
Editeur :
Wiley-VCH
Parution :
2011-08-15
PDF, ePub
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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic...
Editeur :
Wiley
Parution :
2011-08-10
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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Breast cancer is a complex disease caused by multiple environmental and lifestyle factors interacting with genetic susceptibility across the life span. Therefore, environmental factors are of intense interest to both researchers and community members, including women...
Editeur :
Springer
Parution :
2011-08-10
ePub
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The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals.The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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