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Toxicology and Epigenetics



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Éditeur :

Wiley


Paru le : 2012-08-23



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Description

Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical.
Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research.
Topics covered include: environment, epigenetics and diseases DNA methylation and toxicogenomics chromatin at the intersection of disease and therapy epigenomic actions of environmental arsenicals environment, epigenetics and cardiovascular health toxicology, epigenetics and autoimmunity ocular epigenomics: potential sites of environmental impact in development and disease nuclear RNA silencing and related phenomena in animals epigenomics – impact for drug safety sciences methods of global epigenomic profiling transcriptomics: applications in epigenetic toxicology
Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government.
Pages
688 pages
Collection
n.c
Parution
2012-08-23
Marque
Wiley
EAN papier
9781119976097
EAN PDF
9781118349038
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
688
Taille du fichier
6359 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
297,60 €
EAN EPUB
9781118349069
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
688
Taille du fichier
24535 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
297,60 €

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