Téléchargez le livre : Fused Pyrimidine-Based Drug Discovery

Fused Pyrimidine-Based Drug Discovery



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Elsevier Science


Paru le : 2022-10-08



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Description
Fused Pyrimidine-Based Drug Discovery covers all categories of fused-pyrimidines along with pharmacological and in silico studies. It covers the chemistry and biological activities, as well as the design of novel fused-pyrimidine scaffolds. N-Heterocyclic scaffolds are found in most known drug candidates, and are of interest to medicinal and organic chemists to design, synthesize and evaluate their biological properties. A variety of fused-pyrimidine molecules have been synthesized and extracted from natural resources, and are found to exhibit various biological activities such as antifolates, anticancer agents, analgesics, antimetabolites, CNS active agents and many more. Some of these scaffolds like purines are also known to have involvement in biological processes and are part of the framework of genetic material. This book focuses on the classification, structural chemistry, and chemical and physical properties along with various approaches for their synthesis. This book is ideal for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. Covers US FDA approved fused pyrimidine containing drugs and their analyses Comprises classification based upon fusion of carbocyclic/heterocyclic rings(s) with a pyrimidine ring, and features their synthetic schemes, approaches and strategies Includes new fused-pyrimidine scaffolds, allowing the researcher to predict the mechanisms involved in their synthesis Covers fused pyrimidine containing bioactive compounds from the natural sources Covers in silico studies of known fused pyrimidines and Structure-Activity Relationship (SAR), which will encourage the development of new or modified existing scaffolds with specific biological activities

Elsevier Science & Technology
Pages
378 pages
Collection
n.c
Parution
2022-10-08
Marque
Elsevier Science
EAN papier
9780443186165
EAN PDF
9780443186172
Informations sur l'ebook
Nombre pages copiables
37
Nombre pages imprimables
37
Taille du fichier
140964 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
242,00 €
EAN EPUB SANS DRM
9780443186172
Informations sur l'ebook
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
242,00 €

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