Frank Crespilho is Professor of Physical-Chemistry at the Chemistry Institute of University of São Paulo, São Carlos, since 2012. He was Associate Professor of Chemistry at Federal University of ABC, Brazil (2009–2012), Visiting Associate in Chemistry at California Institute of Technology, Caltech (EUA), and Visiting Professor at Max Planck Institute for Solid State Research, Stuttgart, Germany (2016). He was Visiting Professor at Harvard University (2018–2019) at the laboratory of Prof. Michael Aziz, and since 2019, he is Fellow of the J. A. P. School of Engineering and Applied Sciences, Harvard University. He is Coordinator of COVID-19 network in metabolomics and diagnostics chemistry at the University of São Paulo. He was one of the inventors of the “Popular Fast Test of COVID-19”, costing less than a dollar, for mass testing in developing countries. His research interests include fundamental and applied bioelectrochemistry with a distinctive focus on the chemistry ofenergy, life and health. His work combines physical chemical methods and instrumentation development timely application to biological fuel cells and bioinspired batteries, biosensors technology and electron transfer reactions in biological system. His recent work focuses on in situ and operando spectroscopic-electrochemistry elucidation of the electron transfer mechanism involving redox enzyme, proteins, DNA and drug delivery in single cells. He has made contributions on the field of protein immobilization processes on solid surfaces, single cells micro-FTIR analysis, bio-electrocatalysis and coupling analytical tools to resolve electron transfer mechanism in proteins. Dr. Crespilho developed a technique named Electrochemical Coupled Vibrational Spectromicroscopy (EVSM), which consists in a multiplex infrared spectroscopy imaging system for monitoring spatially resolved redox chemistry in bioelectrodes, bioinorganic molecules, biological films and single cells.